Main Street is a street located in the town of Rosewood. This is where all the stores and businesses seen on Pretty Little Liars are found, including:
- Lucky Leon's Cupcakes
- An art gallery
- A bicycle shop
- Eddie's Pizzeria
- Dr. Sullivan's Office (former office)
- The Church
- Lucky Elephant
- COFFEA Espresso Shop
- DiLaurentis Commercial Properties Office
- Speed Demon Express
- Jonathan Simon Antiques
- Veronica Hastings' Law Office
- Laurel Tuckman's Photography Studio
- The Brew